Biologics

Spinal Implants

Clinical Evidence

Advancing Care Through Clinical Evidence

Scientific evidence plays an important role in helping surgeons evaluate biologic technologies and make informed treatment decisions. Explore published clinical papers, peer-reviewed research, case studies, and technical resources supporting Xtant Medical’s regenerative portfolio.
As new evidence continues to emerge, we remain committed to expanding the body of scientific literature that supports our technologies and the surgeons who use them.
Browse the publications below by product or specialty.
Clinical Certifications

Bleazey & Brigido – Reconstruction of Complex Osteochondral Lesions of the Talus

Brigido – Allogeneic Cancellous Bone Sponge for Foot and Ankle Arthrodesis

Protzman – Biologic Augmentation of Foot and Ankle Arthrodeses

Galli – Demineralized Allograft Subchondral Bone in Talar OCD Lesions

Girasole – TLIF Using Titanium Implant and OsteoSponge

Miller – Rationale, Characteristics and Clinical Performance of OsteoSponge

Yoon – DBM Sponges in Posterolateral Lumbar Spine Fusion

Kiely – New Formulation of DBM Putty in Rabbit Fusion Model

Schallenberger – Temperature Exposure on DBM Putty

High lumbar noninstrumented fusion rates using lamina autograft and NanOss/BMA

High posterior cervical fusion rates with iliac autograft and NanOss/BMA

Use of Nanocrystalline Hydroxyapatite With Autologous BMA and Local Bone

NanOss Bioactive versus Vitoss for Lumbar Fusion

Vitoss versus NanOss for Posterior Cervical Fusion

Dang et al. Randomized Controlled Trial

Bruckner et al. Application Techniques of a Novel Hemostat

Cunningham et al.

Chatterjee – American Surgeon

Olano – PRS Tufts Breast Oncoplastic

Bleazey & Brigido – Reconstruction of Complex Osteochondral Lesions of the Talus

Brigido – Allogeneic Cancellous Bone Sponge for Foot and Ankle Arthrodesis

Protzman – Biologic Augmentation of Foot and Ankle Arthrodeses

Galli – Demineralized Allograft Subchondral Bone in Talar OCD Lesions

Girasole – TLIF Using Titanium Implant and OsteoSponge

Yoon – DBM Sponges in Posterolateral Lumbar Spine Fusion

Kiely – New Formulation of DBM Putty in Rabbit Fusion Model

High lumbar noninstrumented fusion rates using lamina autograft and NanOss/BMA

High posterior cervical fusion rates with iliac autograft and NanOss/BMA

Use of Nanocrystalline Hydroxyapatite With Autologous BMA and Local Bone

NanOss Bioactive versus Vitoss for Lumbar Fusion

Vitoss versus NanOss for Posterior Cervical Fusion

Miller – Rationale, Characteristics and Clinical Performance of OsteoSponge

Dang et al. Randomized Controlled Trial

Bruckner et al. Application Techniques of a Novel Hemostat

Chatterjee – American Surgeon

Olano – PRS Tufts Breast Oncoplastic

Schallenberger – Temperature Exposure on DBM Putty